Reaction Biologyでは、下記7種類のキナーゼパネルアッセイを提供しており、毎月定期的にアッセイを実施しています。
Kinase HotSpot™ Assayと同様、Gold StandardのRIによるダイレクトな測定をメインに行っており、高濃度(1 mM)ATP条件下でのアッセイが可能なパネルもございます。

  • Monthly Wild type Kinase Panel (374キナーゼ)
  • Monthly Mutant Kinase Panel (340キナーゼ)
  • Monthly Atypical Kinase Panel (24キナーゼ)
  • Monthly Lipid Kinase Panel (23キナーゼ)
  • Monthly Diacylglycerol Kinase (DGK) Panel (10キナーゼ)
  • ATP-Max KinomeScreen (1 mM ATP, 341キナーゼ)  NEW 
  • ATP-Max Diversify (1 mM ATP, 70キナーゼ)  NEW 

Monthly Wild Type Kinase Panel

Target name
1ABL1
2ABL2/ARG
3ACK1
4AKT1
5AKT2
6AKT3
7ALK
8ALK1/ACVRL1
9ALK2/ACVR1
10ALK3/BMPR1A
11ALK4/ACVR1B
12ALK5/TGFBR1
13ALK6/BMPR1B
14ARAF
15ARK5/NUAK1
16ASK1/MAP3K5
17Aurora A
18Aurora B
19Aurora C
20AXL
21BLK
22BMPR2
23BMX/ETK
24BRAF
25BRK
26BRSK1
27BRSK2
28BTK
29CAMK1a
30CAMK1b
31CAMK1d
32CAMK1g
33CAMK2a
34CAMK2b
35CAMK2d
36CAMK2g
37CAMK4
38CAMKK1
39CAMKK2
40CDC7/DBF4
41CDK1/cyclin A
42CDK1/cyclin B
43CDK1/cyclin E
44CDK2/cyclin A1
45CDK2/cyclin A
46CDK2/cyclin E
47CDK2/cyclin E2
48CDK2/cyclin O
49CDK3/cyclin C
50CDK3/cyclin E
51CDK3/cyclin E2
52CDK4/cyclin D1
53CDK4/cyclin D2
54CDK4/cyclin D3
55CDK5/p25
56CDK5/p35
57CDK6/cyclin D1
58CDK6/cyclin D2
59CDK6/cyclin D3
60CDK7/cyclin H
61CDK9/cyclin K
62CDK9/cyclin T1
63CDK9/cyclin T2
64CDK14 (PFTK1)/cyclin Y
65CDK15/cyclin A2
66CDK15/cyclin B1
67CDK16/cyclin Y
68CDK17/cyclin Y (PCTK2)
69CDK18/cyclin Y
70CHK1
71CHK2
72CK1a1
73CK1a1L
74CK1d
75CK1epsilon
76CK1g1
77CK1g2
78CK1g3
79CK2a
80CK2a2
81c-Kit
82CLK1
83CLK2
84CLK3
85CLK4
86c-MER
87c-MET
88COT1/MAP3K8
89CSK
90c-Src
91CTK/MATK
92DAPK1
93DAPK2
94DCAMKL1
95DCAMKL2
96DCAMKL3
97DDR1
98DDR2
99DMPK
100DMPK2/CDC42BPG
101DRAK1/STK17A
102DYRK1/DYRK1A
103DYRK1B
104DYRK2
105DYRK3
106DYRK4
107EGFR
108EPHA1
109EPHA2
110EPHA3
111EPHA4
112EPHA5
113EPHA6
114EPHA7
115EPHA8
116EPHB1
117EPHB2
118EPHB3
119EPHB4
120ERBB2/HER2
121ERBB4/HER4
122ERK1/MAPK3
123ERK2/MAPK1
124ERK5/MAPK7
125ERK7/MAPK15
126ERN1/IRE1
127ERN2/IRE2
128FAK/PTK2
129FER
130FES/FPS
131FGFR1
132FGFR2
133FGFR3
134FGFR4
135FGR
136FLT1/VEGFR1
137FLT3
138FLT4/VEGFR3
139FMS
140FRK/PTK5
141FYN
142GCK/MAP4K2
143GLK/MAP4K3
144GRK1
145GRK2
146GRK3
147GRK4
148GRK5
149GRK6
150GRK7
151GSK3a
152GSK3b
153Haspin
154HCK
155HGK/MAP4K4
156HIPK1
157HIPK2
158HIPK3
159HIPK4
160HPK1/MAP4K1
161IGF1R
162IKKa/CHUK
163IKKb/IKBKB
164IKKe/IKBKE
165IR
166IRAK1
167IRAK4
168IRR/INSRR
169ITK
170JAK1
171JAK2
172JAK3
173JNK1
174JNK2
175JNK3
176KDR/VEGFR2
177KHS/MAP4K5
178LATS1
179LATS2
180LCK
181LCK2/ICK
182LIMK1
183LIMK2
184LKB1
185LOK/STK10
186LRRK2
187LYN
188LYN B
189MAK
190MAPKAPK2
191MAPKAPK3
192MAPKAPK5/PRAK
193MARK1
194MARK2/PAR-1Ba
195MARK3
196MARK4
197MAST3
198MASTL
199MEK1
200MEK2
201MEK3
202MEK5
203MEKK1
204MEKK2
205MEKK3
206MEKK6
207MELK
208MINK/MINK1
209MKK4
210MKK6
211MKK7
212MLCK/MYLK
213MLCK2/MYLK2
214MLK1/MAP3K9
215MLK2/MAP3K10
216MLK3/MAP3K11
217MLK4
218MNK1
219MNK2
220MRCKa/CDC42BPA
221MRCKb/CDC42BPB
222MSK1/RPS6KA5
223MSK2/RPS6KA4
224MSSK1/STK23
225MST1/STK4
226MST2/STK3
227MST3/STK24
228MST4
229MUSK
230MYLK3
231MYLK4
232MYO3A
233MYO3B
234NEK1
235NEK2
236NEK3
237NEK4
238NEK5
239NEK6
240NEK7
241NEK9
242NEK11
243NIM1
244NLK
245OSR1/OXSR1
246P38a/MAPK14
247P38b/MAPK11
248P38d/MAPK13
249P38g/MAPK12
250p70S6K/RPS6KB1
251p70S6Kb/RPS6KB2
252PAK1
253PAK2
254PAK3
255PAK4
256PAK5
257PAK6
258PASK
259PBK/TOPK
260PDGFRa
261PDGFRb
262PDK1/PDPK1
263PHKg1
264PHKg2
265PIM1
266PIM2
267PIM3
268PKA
269PKAcb
270PKAcg
271PKCa
272PKCb1
273PKCb2
274PKCd
275PKCepsilon
276PKCeta
277PKCg
278PKCiota
279PKCmu/PRKD1
280PKCnu/PRKD3
281PKCtheta
282PKCzeta
283PKD2/PRKD2
284PKG1a
285PKG1b
286PKG2/PRKG2
287PKN1/PRK1
288PKN2/PRK2
289PKN3/PRK3
290PLK1
291PLK2
292PLK3
293PLK4/SAK
294PRKX
295PYK2
296RAF1
297RET
298RIPK2
299RIPK4
300RIPK5
301ROCK1
302ROCK2
303RON/MST1R
304ROS/ROS1
305RSK1
306RSK2
307RSK3
308RSK4
309SBK1
310SGK1
311SGK2
312SGK3/SGKL
313SIK1
314SIK2
315SIK3
316SLK/STK2
317SNARK/NUAK2
318SNRK
319SRMS
320SRPK1
321SRPK2
322SSTK/TSSK6
323STK16
324STK21/CIT
325STK22D/TSSK1
326STK25/YSK1
327STK32A/YANK1
328STK32B/YANK2
329STK32C/YANK3
330STK33
331STK35/CLIK1
332STK38/NDR1
333STK38L/NDR2
334STK39/STLK3
335SYK
336TAK1
337TAOK1
338TAOK2
339TAOK3/JIK
340TBK1
341TEC
342TESK1
343TESK2
344TGFBR2
345TIE2/TEK
346TLK1
347TLK2
348TNIK
349TNK1
350TRKA
351TRKB
352TRKC
353TSSK2
354TSSK3/STK22C
355TSSK4
356TTBK1
357TTBK2
358TXK
359TYK1/LTK
360TYK2
361TYRO3/SKY
362ULK1
363ULK2
364ULK3
365VRK1
366VRK2
367WNK1
368WNK2
369WNK3
370YES/YES1
371YSK4/MAP3K19
372ZAK/MLTK
373ZAP70
374ZIPK/DAPK3

Monthly Mutant Kinase Panel

Target name
1ABL1 (E255K)
2ABL1 (E255V)
3ABL1 (F317I)
4ABL1 (F317L)
5ABL1 (G250E)
6ABL1 (H396P)
7ABL1 (M351T)
8ABL1 (Q252H)
9ABL1 (T315I)
10ABL1 (V299L)
11ABL1 (Y245F)
12ABL1 (Y245F/Y412F)
13ABL1 (Y253F)
14ABL1 (Y253H)
15AKT1 (E17K)
16AKT2 (E17K)
17AKT3 (E17K)
18AKT3 (G171R)
19ALK (C1156Y)
20ALK (L1152R)
21ALK (L1196M)
22ALK (L1196M/G1202R)
23ALK (F1174L)
24ALK (F1174L)-EML4
25ALK (F1174L)-NPM1
26ALK (F1174S)
27ALK (G1202R)
28ALK (G1269A)
29ALK (G1269S)
30ALK (R1275Q)
31ALK (S1206R)
32ALK (T1151M)
33ALK (T1151-L1152insT)
34ALK-EML4 (Eex6Aex20)
35ALK-EML4 (Eex13Aex20)
36ALK-EML4 (Eex14Aex20)
37ALK-EML4 (Eex20Aex20)
38ALK-KIF5B (Kex24Aex20)
39ALK-KLC1 (Kex8Aex20)
40ALK-NPM1
41ALK-STRN (Sex3Aex20)
42ALK-TFG
43ALK-TFG (Tex4Aex20)
44ALK-TPM1
45ALK-TPM3
46ALK2 (Q207D)
47ALK2 (R206H)
48Aurora B (G160L)
49AXL (R499C)
50BRAF (d485-489/P490Y)
51BRAF (G464V)
52BRAF (G469A)
53BRAF (K601E)
54BRAF (L597V)
55BRAF (T599_V600insT)
56BRAF (V599E)
57BRAF (V600A)
58BRAF (V600D)
59BRAF (V600K)
60BRAF (R506_K507insVLR)
61BRAF-FAM131B (Fex2Bex9)
62BRAF-KIAA1549 (Kex15Bex9)
63BRAF-KIAA1549 (Kex16Bex9)
64BRAF-SRGAP3 (Sex12Bex9)
65BTK (C481S)
66BTK (E41K)
67BTK (P190K)
68BTK (T474I)
69BTK (Y485F)
70CHK2 (I157T)
71CK1a1 (E42C)
72CK1a1 (I35C)
73CK1epsilon (R178C)
74c-Kit (d557-558)
75c-Kit (A829P)
76c-Kit (d557-558/Y823D)
77c-Kit (D816E)
78c-Kit (D816F)
79c-Kit (D816H)
80c-Kit (D816I)
81c-Kit (D816V)
82c-Kit (D816Y)
83c-Kit (D820E)
84c-Kit (D820Y)
85c-Kit (N822K)
86c-Kit (T670I)
87c-Kit (V559A)
88c-Kit (V559D)
89c-Kit (V559D/V654A)
90c-Kit (V559D/T670I)
91c-Kit (V560G)
92c-Kit (V560G/D816V)
93c-Kit (V560G/N822K)
94c-Kit (V654A)
95c-Kit (Y823D)
96c-MER (A708S)
97c-MET (D1228A)
98c-MET (D1228G)
99c-MET (D1228H)
100c-MET (D1228N)
101c-MET (D1228V)
102c-MET (D1228Y)
103c-MET (Del Ex14)
104c-MET (R970C)
105c-MET (F1200I)
106c-MET (G1163R)
107c-MET (H1094L)
108c-MET (H1094Y)
109c-MET (K1244R)
110c-MET (L1195F)
111c-MET (L1195V)
112c-MET (M1250I)
113c-MET (M1250T)
114c-MET (P991S)
115c-MET (T992I)
116c-MET (T1173I)
117c-MET (V1092I)
118c-MET (Y1230A)
119c-MET (Y1230C)
120c-MET (Y1230D)
121c-MET (Y1230H)
122c-MET (Y1230S)
123c-MET (Y1235D)
124c-MET-KIF5B (Kex24Mex14)
125c-MET-TFG (Tex5Mex15)
126c-Src (T341M)
127c-SRC (Y530F)
128DDR2 (N456S)
129DDR2 (T654M)
130EGFR (A763_Y764insFHEA)
131EGFR (A763_Y764insFQEA)
132EGFR (A767_S768insTLA)
133EGFR (C775S/T790M/L858R)
134EGFR (C797A)
135EGFR (C797G/L858R)
136EGFR (C797S)
137EGFR (C797S/L858R)
138EGFR (d746)
139EGFR (d746-750)
140EGFR (d746-750/C775S/T790M/L858R)
141EGFR (d746-750/C797A)
142EGFR (d746-750/C797S)
143EGFR (d746-750/G724S)
144EGFR (d746-750/S768I)
145EGFR (d746-750/T790M)
146EGFR (d746-750/T790M/C797S)
147EGFR (d746-750/T790M/C797S/L858R)
148EGFR (d746-750/T790M/L792F)
149EGFR (d746-750/T790M/L792H)
150EGFR (d746-750/T790M/L798I)
151EGFR (d746-750/T790M/L858R)
152EGFR (d747-749)
153EGFR (d747-749/A750P)
154EGFR (d747-752/P753S)
155EGFR (d752-759)
156EGFR (D761Y)
157EGFR (D770GY)
158EGFR (D770_N771insG)
159EGFR (D770_N771insNPG)
160EGFR (D770_N771insNPG/T790M)
161EGFR (G719C)
162EGFR (G719D)
163EGFR (G719S)
164EGFR (K716A)
165EGFR (K716A/C797S/L858R)
166EGFR (K716A/T790M/C797S/L858R)
167EGFR (K716Q/L718Q)
168EGFR (K728A)
169EGFR (K728A/T790M/C797S/L858R)
170EGFR (L718Q)
171EGFR (L747S)
172EGFR (L792F)
173EGFR (L792F/L858R)
174EGFR (L792H)
175EGFR (L792H/C797S/L858R)
176EGFR (L792H/L858R)
177EGFR (L858R)
178EGFR (L861Q)
179EGFR (N771_P772insH)
180EGFR (N771_P772insN)
181EGFR (R999A)
182EGFR (S768I)
183EGFR (T790M)
184EGFR (T790M/C797G/L858R)
185EGFR (T790M/C797S)
186EGFR (T790M/C797S/L858R)
187EGFR (T790M/L858R)
188EGFR (T790M/L792F/L858R)
189EGFR (T790M/L792H/L858R)
190EGFR (T790M/L792F/C797S/L858R)
191EGFR (T790M/L792H/C797S/L858R)
192EGFR (V769_D770insGE)
193EGFR (V948R)
194ERBB2 (A775_G776insYVMA)
195ERBB2 (D769H)
196ERBB2 (D769Y)
197ERBB2 (P780_Y781insGSP)
198ERBB2 (P1170A)
199ERBB2 (R896C)
200ERBB2 (V777L)
201ERBB2 (V777_G778insCG)
202ERBB2 (V956R)
203ERN1/IRE1 (R727A)
204ERN1/IRE1 (R728A)
205ERN1/IRE1 (R727A/R728A)
206FGFR1 (V561M)
207FGFR1 (W666R)
208FGFR1OP-FGFR1
209FGFR2 (C491A)
210FGFR2 (C491F)
211FGFR2 (C491S)
212FGFR2 (C491A/V564I)
213FGFR2 (C491A/V564L)
214FGFR2 (C491S/V564L)
215FGFR2 (E565A)
216FGFR2 (E565G)
217FGFR2 (K526E)
218FGFR2 (K641R)
219FGFR2 (K659N)
220FGFR2 (M420I)
221FGFR2 (N549H)
222FGFR2 (N549K)
223FGFR2 (R612T)
224FGFR2 (V564F)
225FGFR2 (V564I)
226FGFR2 (V564L)
227FGFR3 (V555M)
228FGFR3 (G697C)
229FGFR3 (K650E)
230FGFR3 (K650M)
231FGFR3 (K650Q)
232FGFR4 (N535K)
233FGFR4 (V550E)
234FGFR4 (V550L)
235FGFR4 (V550M)
236FLT3 (D835Y)
237FLT3 (ITD)
238FLT3 (ITD)-NPOS
239FLT3 (ITD)-W51
240FLT3 (F594_R595insR)
241FLT3 (F594_R595insREY)
242FLT3 (F691L/D835Y)
243FLT3 (R595_E596insEY)
244FLT3 (Y591_V592insVDFREYEYD)
245FLT3 (Y591-V592insVDFREYEYD/D835Y)
246FLT3 (Y591-V592insVDFREYEYD/F691L)
247FYN (Y531F)
248JAK2 (V617F)
249LRRK2 (G2019S)
250LRRK2 (I2020T)
251LRRK2 (R1441C)
252MEK1 (P124L)
253MELK (T460M)
254p38a (T106M)
255PAK2 (Y443N)
256PDGFRa (D842V)
257PDGFRa (G680R)
258PDGFRa (T674I)
259PDGFRa-FIP1L1
260PDGFRa (V561D)
261PDGFRb-TPM3
262PKA (L206R)
263PKA-DNAJB1
264PKD2 (G870E)
265PKD2/PRKD2 (G848E)
266PKMzeta
267PKN1-ANXA4 (Aex2Pex13)
268PKN1-TECR (Tex1Pex10)
269RAF1 (R391W)
270RET (A883F)
271RET (E732K)
272RET (E762Q)
273RET (G691S)
274RET (G810C)
275RET (G810R)
276RET (G810S)
277RET (L730I)
278RET (L730M)
279RET (L790F)
280RET (M918T)
281RET (R749T)
282RET (R813Q)
283RET (R912P)
284RET (S891A)
285RET (S904F)
286RET (S904A)
287RET (V738A)
288RET (V778I)
289RET (V804E)
290RET (V804L)
291RET (V804M)
292RET (Y791F)
293RET (Y806C)
294RET (Y806H)
295RET (Y806N)
296RET-BCR
297RET-CCDC6 (PTC1)
298RET-KIF5B (Kex15Rex14)
299RET (V804L)-KIF5B
300RET (V804M)-KIF5B
301RET-PRKAR1A (PTC2)
302RET-NCOA4 (PTC3)
303ROS1 (G2032R)
304ROS1 (G2101A)
305ROS1 (G2101C)
306ROS1-GOPC
307ROS1 (L2086F)
308ROS1-TPM3
309RSK2 (I416V)
310RSK2 (L608F)
311TIE2 (A1124V)
312TIE2 (P883A)
313TIE2 (R849W)
314TIE2 (R915C)
315TIE2 (Y897C)
316TIE2 (Y897H)
317TIE2 (Y897H/R915C)
318TIE2 (Y897S)
319TIE2 (Y1108F)
320TRKA (A608D)
321TRKA (F589L)
322TRKA (G595R)
323TRKA (G595R/A608D)
324TRKA (G595R/L657M)
325TRKA (G595R/G667A)
326TRKA (G595R/G667C)
327TRKA (G595R/G667S)
328TRKA (G667C)
329TRKA (G667S)
330TRKA (L657M)
331TRKA-TFG (TRK-T3)
332TRKA-TPM3
333TRKA-TPR
334TRKC (G623E)
335TRKC (G623R)
336TRKC (G623R/L686M)
337TRKC (G696A)
338TRKC (L686M)
339YES1 (T348I)
340ZAP70 (Y319F)

Monthly Atypical Kinase Panel

Target name
1AMPK(A1/B1/G1)
2AMPK(A1/B1/G2)
3AMPK(A1/B1/G3)
4AMPK(A1/B2/G1)
5AMPK(A1/B2/G2)
6AMPK(A1/B2/G3)
7AMPK(A2/B1/G1)
8AMPK(A2/B1/G2)
9AMPK(A2/B1/G3)
10AMPK(A2/B2/G1)
11AMPK(A2/B2/G2)
12AMPK(A2/B2/G3)
13DNA-PK
14EEF2K
15EIF2AK1/HRI
16EIF2AK2
17EIF2AK3/PERK
18EIF2AK4/GCN2
19mTOR/FRAP1
20PDK1/PDHK1
21PDK2/PDHK2
22PDK3/PDHK3
23PDK4/PDHK4
24TRPM7/CHAK1

Monthly Lipid Kinase Panel

Target name
1PI3K (p110a(E542K)/p85a)
2PI3K (p110a(E545K)/p85a)
3PI3K (p110a(H1047R)/p85a)
4PI3K (p110a/p65a)
5PI3Ka (p110a/p85a)
6PI3Kb (p110b/p85a)
7PI3Kd (p110d/p85a)
8PI3Kg (p120g)
9PI3KC2a/PIK3C2A
10PI3KC2b/PIK3C2B
11PI3KC3
12PI4K2A
13PI4Ka
14PI4Kb
15PIP5K1A
16PIP5K1B
17PIP5K1C
18SPHK1
19SPHK2
20PIP4K2A/PIP5K2A
21PIP4K2B/PIP5K2B
22PIP4K2C/PIP5K2C
23PIP5K3/PYKFYVE

Monthly Diacylglycerol Kinase Panel

Target name
1DGKA
2DGKB
3DGKD
4DGKE
5DGKG
6DGKH
7DGKI
8DGKK
9DGKQ
10DGKZ

ATP-Max KinomeScreen

生理学的環境により近い高濃度ATP(1 mM)条件下での、HotSpot™(RI)アッセイを行います。 NEW
Target name
1ABL1
2ABL2/ARG
3ACK1
4AKT1
5AKT2
6AKT3
7ALK
8ALK4/ACVR1B
9ALK5/TGFBR1
10ALK6/BMPR1B
11ARAF
12ARK5/NUAK1
13ASK1/MAP3K5
14AURORA A
15AURORA B
16AURORA C
17AXL
18BLK
19BMPR2
20BMX/ETK
21BRAF
22BRK
23BRSK1
24BRSK2
25BTK
26CAMK1A
27CAMK1B
28CAMK1D
29CAMK1g
30CAMK2a
31CAMK2b
32CAMK2D
33CAMK2G
34CAMK4
35CAMKK2
36CDK1/CYCLIN A
37CDK1/CYCLIN B
38CDK1/CYCLIN E
39CDK14/CYCLIN Y (PFTK1)
40CDK15/CYCLIN A2
41CDK15/CYCLIN B1
42CDK16/CYCLIN Y (PCTAIRE)
43CDK17/CYCLIN Y (PCTK2)
44CDK18/CYCLIN Y (PCTK3)
45CDK2/CYCLIN A
46CDK2/CYCLIN A1
47CDK2/CYCLIN E
48CDK2/CYCLIN E2
49CDK2/CYCLIN O
50CDK3/CYCLIN C
51CDK3/CYCLIN E
52CDK3/CYCLIN E2
53CDK4/CYCLIN D1
54CDK4/CYCLIN D2
55CDK4/CYCLIN D3
56CDK5/P25
57CDK5/P35
58CDK6/CYCLIN D1
59CDK6/CYCLIN D2
60CDK6/CYCLIN D3
61CDK7/CYCLIN H
62CDK9/CYCLIN K
63CDK9/CYCLIN T1
64CDK9/CYCLIN T2
65CHK1
66CHK2
67CK1A1
68CK1A1L
69CK1D
70CK1EPSILON
71CK1G1
72CK1g2
73CK1g3
74CK2A
75CK2A2
76C-KIT
77CLK1
78CLK2
79CLK3
80CLK4
81C-MER
82C-MET
83COT1/MAP3K8
84CSK
85C-SRC
86CTK/MATK
87DAPK1
88DAPK2
89DCAMKL1
90DCAMKL2
91DDR2
92DMPK2
93DYRK1/DYRK1A
94DYRK1B
95DYRK2
96DYRK3
97EGFR
98EPHA1
99EPHA2
100EPHA3
101EPHA4
102EPHA5
103EPHA6
104EPHA7
105EPHA8
106EPHB1
107EPHB2
108EPHB3
109EPHB4
110ERBB2/HER2
111ERBB4/HER4
112ERK1
113ERK2/MAPK1
114ERK5/MAPK7
115ERK7/MAPK15
116ERN1/IRE1
117ERN2/IRE2
118FAK/PTK2
119FER
120FES/FPS
121FGFR1
122FGFR2
123FGFR3
124FGFR4
125FGR
126FLT1/VEGFR1
127FLT3
128FLT4/VEGFR3
129FMS
130FRK/PTK5
131FYN
132GCK/MAP4K2
133GLK/MAP4K3
134GRK2
135GRK3
136GRK4
137GRK5
138GRK6
139GRK7
140GSK3A
141GSK3B
142HASPIN
143HCK
144HGK/MAP4K4
145HIPK1
146HIPK2
147HIPK3
148HIPK4
149HPK1/MAP4K1
150IGF1R
151IKKb/IKBKB
152IKKE/IKBKE
153IR
154IRAK1
155IRAK4
156IRR/INSRR
157ITK
158JAK1
159JAK2
160JAK3
161JNK1
162JNK2
163JNK3
164KDR/VEGFR2
165KHS/MAP4K5
166LATS1
167LATS2
168LCK
169LCK2/ICK
170LIMK1
171LIMK2
172LKB1
173LOK/STK10
174LRRK2
175LYN
176LYN B
177MAK
178MAPKAPK2
179MAPKAPK3
180MAPKAPK5/PRAK
181MARK1
182MARK2/PAR-1BA
183MARK3
184MARK4
185MAST3
186MASTL
187MEK1
188MEK3
189MEK5
190MEKK1
191MEKK2
192MEKK3
193MELK
194MINK/MINK1
195MKK4
196MKK6
197MKK7
198MLCK/MYLK
199MLCK2/MYLK2
200MLK1/MAP3K9
201MLK2/MAP3K10
202MLK3/MAP3K11
203MLK4
204MNK1
205MNK2
206MRCKa/CDC42BPA
207MRCKb/CDC42BPB
208MSK1/RPS6KA5
209MSK2/RPS6KA4
210MSSK1/STK23
211MST1/STK4
212MST2/STK3
213MST3/STK24
214MUSK
215MYLK3
216MYLK4
217MYO3A
218MYO3B
219NEK1
220NEK2
221NEK3
222NEK4
223NEK5
224NEK6
225NEK7
226NEK9
227NIM1
228OSR1/OXSR1
229P38A/MAPK14
230P38B/MAPK11
231P38d/MAPK13
232P38G
233P70S6K/RPS6KB1
234P70S6KB/RPS6KB2
235PAK1
236PAK2
237PAK3
238PAK4
239PAK5
240PAK6
241PASK
242PBK/TOPK
243PDGFRA
244PDGFRB
245PDK1/PDPK1
246PHKG1
247PHKG2
248PIM1
249PIM2
250PIM3
251PKA
252PKAcb
253PKACG
254PKCA
255PKCB1
256PKCB2
257PKCD
258PKCEPSILON
259PKCETA
260PKCG
261PKCIOTA
262PKCMU/PRKD1
263PKCNU/PRKD3
264PKCTHETA
265PKCZETA
266PKD2/PRKD2
267PKG1a
268PKG1B
269PKG2/PRKG2
270PKN1/PRK1
271PLK1
272PLK2
273PLK3
274PRKX
275PYK2
276RAF1
277RET
278RIPK2
279RIPK4
280RIPK5
281ROCK1
282ROCK2
283RON/MST1R
284ROS/ROS1
285RSK1
286RSK2
287RSK3
288RSK4
289SGK1
290SGK2
291SGK3/SGKL
292SIK1
293SIK2
294SIK3
295SLK/STK2
296SNARK/NUAK2
297SNRK
298SRMS
299SRPK1
300SRPK2
301STK21/CIT
302STK22D/TSSK1
303STK25/YSK1
304STK32B/YANK2
305STK38/NDR1
306STK38L/NDR2
307STK39/STLK3
308SYK
309TAOK1
310TAOK2/TAO1
311TAOK3/JIK
312TBK1
313TEC
314TESK1
315TESK2
316TGFBR2
317TIE2/TEK
318TLK1
319TLK2
320TNIK
321TRKA
322TRKB
323TRKC
324TSSK2
325TSSK3/STK22C
326TTBK1
327TTBK2
328TXK
329TYK1/LTK
330TYK2
331TYRO3/SKY
332ULK1
333ULK2
334ULK3
335VRK2
336WNK3
337YES/YES1
338YSK4/MAP3K19
339ZAK/MLTK
340ZAP70
341ZIPK/DAPK3

ATP-Max Diversify

様々なファミリーのKinaseに対して、生理学的環境により近い高濃度ATP(1 mM)条件下でアッセイが可能です。 NEW
Target nameAssay format
1Abl1HotSpot™
2Akt1HotSpot™
3ALK4/ACVT1BHotSpot™
4ARK5/NUAK1HotSpot™
5AurAHotSpot™
6BrafHotSpot™
7BTKHotSpot™
8CaMK1aHotSpot™
9CDK1/Cyclin BHotSpot™
10CDK4/Cyclin D1HotSpot™
11CDK7/Cyclin HHotSpot™
12CDK9/Cyclin T2HotSpot™
13CHK1HotSpot™
14CK1alpha1HotSpot™
15CK1gamma1HotSpot™
16CK2aHotSpot™
17C-KITHotSpot™
18CLK2HotSpot™
19C-METHotSpot™
20c-SRCHotSpot™
21DAPK2HotSpot™
22DCAMKL1HotSpot™
23DYRK1AHotSpot™
24EGFRHotSpot™
25EphA5HotSpot™
26EphB2HotSpot™
27ERK1HotSpot™
28FGFR2HotSpot™
29FLT1/VEGFR1HotSpot™
30FLT3HotSpot™
31GSK3bHotSpot™
32HIPK2HotSpot™
33IGF1RHotSpot™
34IKKe/IKBKeHotSpot™
35IRAK4HotSpot™
36JAK2HotSpot™
37JNK3HotSpot™
38LIMK1HotSpot™
39LOK /STK10HotSpot™
40LYNHotSpot™
41MARK2/PAR-1BaHotSpot™
42MAST3HotSpot™
43MEK1HotSpot™
44MEKK1HotSpot™
45MLK1 /MAP3K9HotSpot™
46MNK2HotSpot™
47MSK2/RPS6KA4HotSpot™
48MST1 /STK4HotSpot™
49MYLK3 (caMLCK)HotSpot™
50NEK1HotSpot™
51p38a/MAPK14HotSpot™
52p70S6RPS6KB1KHotSpot™
53PAK4HotSpot™
54PIM3HotSpot™
55PKAHotSpot™
56PKCaHotSpot™
57PKCthetaHotSpot™
58PLK1HotSpot™
59RETHotSpot™
60ROCK1HotSpot™
61RSK1HotSpot™
62STK22D/TSSK1HotSpot™
63TECHotSpot™
64TGFbR2HotSpot™
65TRkAHotSpot™
66ULK1HotSpot™
67PI3Kalpha (p110a/p85a)ADP-Glo™
68PI3Kbeta (p110b/p85a)ADP-Glo™
69PI3Kdelta (p110d/p85a)ADP-Glo™
70PI3Kgamma(p110d/p85a)ADP-Glo™